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About the study

Stroke is one of the top three causes of disability. Treatments that improve recovery after stroke are lacking. A recent small study suggested that the antidepressant drug, fluoxetine, may improve the recovery of strength in stroke patients with limb weakness. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aims to find out whether fluoxetine, given in the first two weeks after stroke to 1600 participants, and continued for 6 months, is safe and improves recovery at 6 months compared to a placebo.

Recruitment Progress

Recruitment target: 1600 participants
Total affinity patients randomised to date is: 544
Total participants on the MRI Sub Study: 8
Total participants on the DNA Sub Study: 31


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Supported By:

NHMRC